Clemson moved back into second place in the ACC Atlantic Division standings as a result of the Tigers' 3-2, 11-inning victory over Pittsburgh Friday, coupled with Florida State's 7-1 win over Wake Forest at Winston-Salem.
The Tigers (23-14, 11-7) will go for the series victory today at 3 p.m. when they face the Panthers (16-21, 8-11) at Charles Cost Field in Pittsburgh.
Daniel Gossett will be on the mound for the Tigers against Pitt's Matt Wotherspoon in a battle of righthanders.
The Deacons (24-16, 11-8) dropped half a game behind the Tigers, while Florida State improved to 29-8 overall and 15-4 in conference play.
Also winning by 3-2 margins on Friday were Duke (22-17, 10-9) over Virginia Tech (18-18-1, 7-12) and top-ranked Virginia (31-6, 15-4) over North Carolina (22-16, 9-10).
NC State (21-15, 7-12) won its opener over Boston College (12-25, 3-16) by a score of 5-1, while Maryland (23-13, 8-10) topped Georgia Tech (24-15, 10-9) by a 7-2 margin.
Miami (26-12, 14-4) will go for its 14th straight victory when the Hurricanes open their weekend series against Notre Dame (15-21, 3-15).