Trouble spots for the Tigers...
QB Sean Renfree: He's one of the ACC's most experienced and effective quarterbacks, and is the league's career leader in passing yardage, completions and attempts. He has nine 300-yard games in his career, and completed 70 percent or more of his passes in five of Duke's first seven games this season. If he can't play against the Tigers, will be a huge blow for the Blue Devils.
WR Conner Vernon: The ACC's all-time leading pass catcher, he entered the FSU game needing just 94 yards to surpass former Seminoles' star Peter Warrick as the ACC's reception yardage record holder (3,517), but was held to just three catches for 12 yards. He leads all active FBS players in receptions and reception yardage. He's caught at least one pass in 44 straight games, and 10 or more passes on four occasions.
WRs Jamison Crowder & Desmond Scott: Both rank in the top six in the ACC in receptions per game.
PK Ross Martin: He leads the nation's freshman kickers in scoring with 8.3 points per game, and has made 14 of 16 field goal attempts and all 34 PATs this season.
P Will Monday: Another freshman, he leads the ACC with his 44.5 punting average, and already has 15 punts of 50 yards or more.
RBs Jela Duncan & Josh Snead: Both running backs punished North Carolina's defense - 74 yards and ACC rookie of the week honors for Duncan, and 99 yards for Snead.
C Brian Moore: He's a veteran of 36 career starts and more than 2,500 snaps, and is, like Clemson's Dalton Freeman, a Rimington Award candidate.
CB Ross Cockrell: He ranks eighth nationally in passes defended with 15, including an ACC-leading four interceptions.
DBs Walt Canty & Jordan Byas: Like Cockrell, both have been honored this season as ACC defensive back of the week.
DE Kenny Anunike: He ranks sixth in the ACC in sacks with five, and has had nine sacks and 11 tackles for loss in his last 12 games.